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PUBLICATIONS

Scientific articles

 

A novel single domain in HIV-1 Nef is required for Lck binding, CD4 downregulation and Nef-enhanced optimal infectivity. Submitted to PLos Pathogens.
Martinez-Bonet M and MADRID R.


Validation of a Generation 4 Phosphorus-Containing Polycationic Dendrimer for Gene Delivery against HIV-1. Current Medicinal Chemistry 2012.
Briz V., Serramía MJ., Madrid R., Turrin CO., Caminade AM., Majoral JP., and Muñoz-Fernández M.Á.

 

Carbosilane dendrimers as carriers of siRNA. J. Drug Deliv. Sci. Tech., 2012.
Jiménez J.L., Gómez R., Briz V., Madrid R., Bryszews M., de la Mata F.J., and  Muñoz-Fernández M.Á.

 

The formin INF2 regulates basolateral-to-apical transcytosis and lumen formation in association with Cdc42 and MAL2. Developmental Cell. 2010.
MADRID R*, Aranda JF, Rodríguez-Fratichelli AE, Ventimiglia, L, Andres-Delgado L, Shehata M, Fanayan S, Gomez S, Jiménez A, Martin-Belmonte F, Byrne JA, and Alonso MA*.

 

Formin INF2 regulates MAL-mediated transport of Lck to the plasma membrane of human T lymphocytes. Blood 2010.
Andrés-Delgado A, Antón OM, MADRID R, Byrne, J and Alonso MA.

 

The phospholipid scramblases 1 and 4 are cellular receptors for the secretory leukocyte protease inhibitor and interact with CD4 at the plasma membrane. PLos ONE. 2009.
Py B, Basmaciogullari S, Zarka M, Moura IC, Benhamou M, Monteiro RC, Hocini, H, Bouchet J, MADRID R, and Benichou S.

 

The Diaphanous Related Formin FHOD1 Associates with ROCK1 and Promotes Src-dependent Plasma Membrane Blebbing J.Biol. Chem. 2008.
Hannemann, S, MADRID, R, Stastna, J, Kitzing, T, Gasteier, J, Schönichen, A, Bouchet, J, Jimenez, A, Geyer, M, Grosse, R, Benichou, S and Fackler O T.

 

Modulation of Cellular Protein Trafficking by Human Immunodeficiency Virus Type- 1 Nef: Role of the Acidic Residue in the ExxxLL Motif. Virology  2006.
Coleman, SH, MADRID, R, Van Damme, N, Mitchell, RS, Bouchet, J, Servant, C, Pillai, S, Benichou, S, and Guatelli, JC.

 

FHOD1 Coordinates Actin Filament and Microtubule Alignment to Mediate Cell Elongation. Exp. Cell Res. 2005.
Gasteier JE, Schroeder S, Muranyi W, MADRID R, Benichou S, and Fackler OT.

 

Oligomerization of the Diaphanous-Related Formin FHOD1 Requires a Coiled-coil Motif Critical for its Cytoskeletal and Transcriptional Activities. FEBS Lett. 2005.
MADRID R, Gasteier JE, Bouchet J, Schroder S, Geyer M, Benichou S, and Fackler OT.

 

Nef-induced Alteration of the Early/Recycling Endosomal Compartment Correlates with Enhancement of HIV-1 Infectivity. J Biol Chem. 2005.
MADRID R, Janvier K, Hitchin D, Day J, Coleman S, Noviello C, Bouchet J, Benmerah A, Guatelli J, Benichou S.

 

Leucine-Specific, Functional Interactions Between Human Immunodeficiency Virus Type 1 Nef and Adaptor Protein Complexes. J Virol. 2005.
Coleman SH, Van Damme N, Day JR, Noviello CM, Hitchin D, MADRID R, Benichou S, and Guatelli JC.

 

Activation of the Rac-Binding Partner FHOD1 Induces actin Stress Fibers via a ROCK-Dependent Mechanism. J Biol Chem. 2003.
Gasteier JE, MADRID R, Krautkramer E, Schroder S, Muranyi W, Benichou S, and Fackler OT.

 

HIV-1 Nef Stabilizes the Association of Adaptor Protein Complexes type 1 and 3 with Membranes. J. Biol. Chem. 2003.
Janvier K, Craig H, Hitchin D, MADRID R, Sol-Foulon N, Renault L, Cherfils J, Cassel D, Benichou S and Guatelli J.

 

Polarized Trafficking and Surface Expression of the AQP4 Water Channel are Coordinated by Serial and Regulated Interactions with Different Clathrin-Adaptor Complexes. EMBO J.2001.
MADRID R, Le Maout S, Barrault MB, Janvier K, Benichou, S. and Mérot J.

 

Individual functions of the HAK and TRK potassium transporters of Schwanniomyces occidentalis. Mol. Microbiol, 2000.
MADRID R*, Bañuelos MA*, and Rodriguez-Navarro A.

 

Two distinct signals determine the basolateral targeting of AQP4 in the renal epithelial cell line MDCK. Molecular Biology and Physiology of water and Solute Transport. (Hohmann, S and Nielsen S, eds) pp.159-165. Kluwer Academic/Plenun Publishers.2000.
MADRID R, Le Maout S, Barrault MB. and Mérot J.

 

Ectopic potassium uptake in trk1trk2 mutants of Saccharomyces cerevisiae correlates with a hyperpolaryzed plasma membrane. J. Biol. Chem. 1998.
MADRID R, Gómez MJ, Ramos J. and Rodriguez‑Navarro A.

Patents and Utility Models

 

Scramblase/CD4 interaction inhibitors for the treatment of Lentivirus infections. BIO 06036 – BENICHOU. INSERM (FRANCE)
Benichou S., Py B., Basmaciogullari S., Bouchet J, Deprez B, and MADRID R.